University of Dundee

"Syntax in C. elegans locomotion"

Event Date: 
Monday, January 18, 2016 - 14:00
Event Location: 
MSI Small Lecture Theatre
Event Speaker: 
Dr Andre Brown
Institution: 
MRC Clinical Sciences Centre, Imperial College London
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Event Type: 
Seminar

Abstract

We have used inexpensive tracking microscopes to record the spontaneous behaviour of more than 10 000 worms from more than 330 strains, including mutants and wild isolates, at high resolution.  In the context of this data set, I will address two interrelated questions: how can we develop a framework for understanding behaviour quantitatively and how can we use this framework to advance behavioural genetics and phenotypic screening?  Specifically, I will discuss unsupervised methods for detecting stereotyped behaviours and how these can be used for quantitative phenotypic comparisons and investigating behavioural adaptation and evolution.