University of Dundee

"Predictive models of bacterial response and the evolution of resistance to antibiotics"

Event Date: 
Friday, January 24, 2020 - 11:00
Event Location: 
School of Life Sciences, MSI Small Lecture Theatre
Host: 
Dr Rastko Sknepnek
Event Speaker: 
Dr Bartlomiej Waclaw
Institution: 
University of Edinburgh
Event Type: 
Seminar
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The emergence of antibiotic-resistant microorganisms is a global
problem. Despite significant advances in our understanding of molecular
mechanisms of resistance, quantitative models that could predict the response
of bacterial populations to antibiotic treatment are rare. 
 
I will present our attempts at constructing such predictive models. I will first
discuss experimental approaches that we use to understand short- and long-time
bacterial response to antibiotics. I will then show how the experiments can be
understood using physics-inspired models. Finally, I will discuss how these models
can be used to test different biological hypotheses about the emergence of antibiotic.