29 Aug 2019
Hannah Tovell a PhD student in Dario Alessi lab working in collaboration with Claire Crafter (AstraZeneca) and Alessio Ciulli and Andrea Testa in his lab have elaborated a compound that we have termed SGK3-PROTAC1 that induces selective degradation of SGK3 protein kinase. Hannah was able to show that SGK3-PROTAC1 suppressed proliferation of ZR-75-1 and CAMA-1 cancer cell lines treated with a PI3K inhibitor (GDC0941) more effectively than could be achieved by a conventional SGK isoform inhibitor (14H), underscoring the benefit of the PROTAC approach.
16 Aug 2019
Over 50 undergraduate students have been undertaking life science summer projects within the University over the past few months. They presented their research projects at the Annual Summer School Symposium that took place on Wednesday 14th and Thursday 15th August.
06 Aug 2019
The School of Life Sciences is the latest recipient of two new state of the art electric bikes thanks to funding from the Energy Saving Trust in partnership with Transport Scotland. These two additional bikes will complement the existing cycle pool which was first established at the University ten years ago. Trudy Cunningham University of Dundee's Environmental and Sustainability Officer explained, "As well as forming part of the University’s commitment to reduce carbon emissions and encourage sustainable travel.