Latest News for 11/2019
07 Oct 2019
Scientists at the University of Dundee have carried out one of the most comprehensive studies into how immune cells sense and respond to their environment to fight infection and destroy tumours. The research team, who have published their findings in the journal Nature Immunology, said the results provide important insights into how immune responses might be manipulated for the treatment of autoimmune diseases and cancer.
05 Sep 2019
Professor Angus Lamond has been appointed as the 2019-20 British Society for Proteomics Research (BSPR) Lecturer. In this role, the BSPR provides funding to allow Angus to present seminars at Universities and Institutes around the UK to promote research using proteomics technology. As the BSPR Lecturer, Angus is presenting lectures that build on his interests in applying multidimensional proteomics and data science technologies to characterise biological systems and disease mechanisms.
07 Dec 2018
Platinum Informatics, a spin-out company from the University of Dundee, was one of the big winners at the Scottish EDGE Awards last night (December 6), receiving £100,000. Platinum Informatics provides state of the art software solutions for the management, visualisation and analysis of large and complex data sets in a wide range of laboratory and industrial environments. The company is commercialising software developed for more than ten years within the University of Dundee by Professor Angus Lamond’s team in the School of Life Sciences.
06 Sep 2018
The newest spin-out company from the School, Platinum Informatics Ltd, has already been recognised by Converge Challenge who aim to create a new generation of entrepreneurs in Scotland. The company founded by Professor Angus Lamond and Rob Kent has made the final for the Converge Challenge award category for those with an established idea. The company looks to maximise the efficiency and productivity of the modern workplace by enabling access to Big Data Technology.
New methodology for isolating polysomes and other large subcellular structures developed by Lamond...14 Aug 2018
The Lamond laboratory have developed an efficient and highly reproducible new methodology for isolating polysomes and other large subcellular structures, termed ‘Ribo Mega-SEC’, which they have used to study protein translation complexes in cell lines and tissues.
12 Jun 2018
A new study entitled “Proteomic Analysis of the Cell Cycle of Procylic Form Trypanosoma brucei” has just been published in Molecular and Cellular Proteomics (Crozier et al., 2018, Mol Cell Proteomics 2018 17: 1184-1195). This study resulted from a collaboration between the laboratories of Mike Ferguson (BCDD) and Angus Lamond (GRE). Trypanosoma brucei is an evolutionarily divergent eukaryotic protozoan parasite that causes human and animal trypanosomiasis (also called ‘sleeping sickness’) in sub-Saharan Africa.
01 May 2018
Platinum Informatics is a new spin-out company providing state of the art software solutions for the management, visualisation and analysis of large and complex data sets in a wide range of laboratory and industrial environments. The company is commercialising software developed for more than 10 years within the University of Dundee by Professor Angus Lamond’s team in the School of Life Sciences.
Lamond and Watt groups identify key role of specific protein phosphatases in human skin stem cell...13 Nov 2017
A collaboration between the Lamond and Watt groups identifies a key role of specific protein phosphatases in human skin stem cell commitment to differentiation.
23 Oct 2017
In a publication in eLife, Ly et al. report a workflow combining FACS and MS-based proteomics to analyse protein abundance and phosphorylation changes proteome-wide across the mitotic cell division cycle, including resolution of mitotic subphases. The approach, called PRIMMUS or proteomics of intracellular immunolabelled cell subsets, combines intracellular immunostaining, FACS, and mass spectrometry to isolate and analyse cell subsets defined by intracellular markers of cell cycle progression.
29 Sep 2017
A new article from the Lamond group, published in eLife, reports the identification of the plant biflavone, hinokiflavone, as a pre-mRNA splicing modulator (Pawellek et al., 2017). In collaboration with Ron Hay’s group in GRE and the group of Richard Hartley, (University of Glasgow), they show that both natural and synthetic hinokiflavone inhibits splicing in vitro by blocking spliceosome assembly, specifically preventing progression from the spliceosome complex A to complex B.