29 Aug 2019
Hannah Tovell a PhD student in Dario Alessi lab working in collaboration with Claire Crafter (AstraZeneca) and Alessio Ciulli and Andrea Testa in his lab have elaborated a compound that we have termed SGK3-PROTAC1 that induces selective degradation of SGK3 protein kinase. Hannah was able to show that SGK3-PROTAC1 suppressed proliferation of ZR-75-1 and CAMA-1 cancer cell lines treated with a PI3K inhibitor (GDC0941) more effectively than could be achieved by a conventional SGK isoform inhibitor (14H), underscoring the benefit of the PROTAC approach.
16 Aug 2019
Over 50 undergraduate students have been undertaking life science summer projects within the University over the past few months. They presented their research projects at the Annual Summer School Symposium that took place on Wednesday 14th and Thursday 15th August.
06 Aug 2019
The School of Life Sciences is the latest recipient of two new state of the art electric bikes thanks to funding from the Energy Saving Trust in partnership with Transport Scotland. These two additional bikes will complement the existing cycle pool which was first established at the University ten years ago. Trudy Cunningham University of Dundee's Environmental and Sustainability Officer explained, "As well as forming part of the University’s commitment to reduce carbon emissions and encourage sustainable travel.
31 Jul 2019
Researchers in the Medical Research Council Protein Phosphorylation and Ubiquitylation Unit (MRC PPU) have solved one of the mysteries of cell division, a discovery which may shed light on cancer development and one day help develop new drugs to treat the disease.
29 Jul 2019
Food security and livelihoods for a majority of Ethiopians depends on smallholder farming, and barley is an important crop grown by over 4 million smallholder farmers for multiple uses as food, feed and as a cash crop for an emerging malting and brewing industry.
26 Jul 2019
Potatoes have been a staple of Britain’s diet for half a millennium, but new research suggests that limited genetic differences in potato lineages has left British and American spuds vulnerable to the disease that caused the Irish potato famine. Plant scientists at the University of Dundee and the James Hutton Institute have revealed that commercial potato crops are under constant threat of late blight, the pathogen behind one of Europe’s most devastating famines, but wild potato genes might be the cure.
25 Jul 2019
Dr Susan Wyllie, Head of the Mode of Action (MoA) group, has been promoted to tenure track Principal Investigator in the School. Her group is part of the Division of Biological Chemistry and Drug Discovery (BCDD) and the Wellcome Centre for Anti-Infectives Research (WCAIR). Background
24 Jul 2019
The Schools of Life Sciences and Medicine are delighted to host eight of our undergraduate students who are undertaking Medical Research Scotland funded vacation scholarships with researchers in the Schools. These scholarships have the additional challenge of requiring the PI and student to apply for funding together.
23 Jul 2019
Following on from the University wide announcement about Dundee’s overall success in the National Student Survey 2019, further details at the subject level have now been revealed. Our Biological and Biomedical Sciences programmes have again improved in position across our degrees offered through the Schools of Life Sciences and Medicine, recording an increase in overall satisfaction to a new high of 94%.
11 Jul 2019
Researchers from the Drug Discovery Unit have been awarded the “Project of the Year 2018” from Medicines for Malaria Venture (MMV) for their discovery work on potential new drugs for malaria. The annual award goes to the scientific partners involved in that year’s most exciting project from the MMV portfolio. MMV is the world’s leading product development partnership (PDP) for discovering and developing new effective and affordable medicines to treat malaria.