A protocol for utilizing human peripheral blood neutrophils for research into the Parkinson’s disease associated LRRK2 kinase has been published. The collaborative work led by Esther Sammler, Clinical Programme Leader in the Medical Research Council Protein Phosphorylation and Ubiquitylation Unit in the School and Clinical Senior Lecturer & Honorary Consultant in the School of Medicine.
Cell Signalling and Immunology
Alan Prescott has been chosen to be the regional (Europe) EMEA winner of the Olympus Image of the Year Award 2019. This was for the submitted image with the title "The mouse’s whiskers: image from a frozen section of the head from the mito-QC mouse."
This win follows a very successful 12 months where Alan’s microscopy work has been recognised in five other national and international competitions.
A pioneering collaboration between the UK Dementia Research Institute (DRI) and the Medical Research Council’s Protein Phosphorylation and Ubiquitylation Unit (MRC PPU) will use the very latest advances in technology to study rare cell populations and the role of proteins in diseases such as Alzheimer’s and Parkinson’s.
New research has deciphered how rogue communications in blood stem cells can cause Leukaemia. The discovery, published in the journal Science, could pave the way for new, targeted medical treatments that block this process. Blood cancers like leukaemia occur when mutations in stem cells cause them to produce too many blood cells.
University of Dundee researchers have shown how a natural product derived from a group of fungi that has inspired horror novels, movies and computer games works to switch on a protein known to affect cancer cells.
Dr. Henry McSorley has joined the School this month as a member of the Division on Cell Signalling and Immunology. He will be joint deputy head of division alongside Hari Hundal.
Researchers in the Moraga group report the engineering of new tools to manipulate the immune response with the potential to treat human disorders. The research was done in collaboration with the Kazemian group (Purdue University, USA) and Mitra group (Centre de Recherche Jean-Pierre Aubert, France). The research was published in the journal eLife.