During lockdown, the School of Life Sciences at the University of Dundee was not closed. Work continued albeit on a much smaller scale than usual, with the majority of the ongoing research focussed on coronavirus. Our support staff were absolutely critical in keeping the research complex functioning to allow this important work to happen. As we have entered phase 2 of the Scottish Government’s route map out of lockdown, we look back over the past few months and the challenges that our community in the School encountered and had to overcome.
Drug Discovery Unit
The School of Life Sciences at the University of Dundee is a world-class academic institution with a reputation for the excellence of its research, its high quality teaching and student experience, and the strong impact of its activities outside academia. With 900 staff from over 60 countries worldwide the School provides a dynamic, multi-national, collegiate and diverse environment with state-of-the-art laboratory, technology and teaching facilities.
The University of Dundee’s Drug Discovery Unit (DDU) has received €5 million of funding to develop antiviral treatments for Covid-19 and future coronaviruses.
The Universities of Glasgow and Dundee have been awarded £225,000 to rapidly screen for potential COVID-19 treatments.
The project is funded by the COVID-19 Therapeutics Accelerator, an initiative launched by the Bill & Melinda Gates Foundation, Wellcome, and Mastercard to speed up the response to the COVID-19 pandemic by funding the identification, assessment, development and scale up of treatments.
Back in October 2013 Medicines for Malaria Venture (MMV) selected a compound designed and developed at the Drug Discovery Unit (DDU), University of Dundee to enter preclinical development. In June 2015, the discovery, properties and mode of action of the compound DDD107498 were published in the journal Nature.
We are seeking a highly motivated and expert medicinal chemist for a key leadership role. The successful applicant will lead our coronavirus drug discovery programme, setting strategy, and ensuring goals and milestones are met. The appointee will lead, and drive interactions between the programme’s medicinal chemists, biologists, computational chemists and the drug metabolism & pharmacokinetics experts within the Drug Discovery Unit (DDU) team.
The University of Dundee is working with partners around the world as part of an expanding effort to rapidly repurpose existing drugs against Covid-19.
An international research network established by Scripps Research centres around ReFRAME, the world’s leading collection of drugs known to be safe in humans.
The network of collaborating scientific laboratories is aiming to leverage ReFRAME to find antiviral compounds against the novel coronavirus.
University of Dundee researchers are studying a protein that aids the spread of COVID-19 in the hope of finding ways of blocking its function.
The team, from the University’s Medical Research Council Protein Phosphorylation and Ubiquitylation Unit (MRC-PPU) are working in partnership with the Drug Discovery Unit (DDU) to study an enzyme found within the SARS-CoV-2 virus that causes COVID-19 infection.
The University of Dundee has helped establish Scotland’s central COVID-19 testing facility in support of the national response to the coronavirus pandemic.
The centre, based at the University of Glasgow, was announced by the UK Government yesterday as part of a series of measures to increase testing and response to the spread of COVID-19 across the UK. It will be opened in collaboration with the Scottish Government and industry experts from BioAscent Discovery Ltd and Dundee’s Drug Discovery Unit (DDU).