University of Dundee

Medical Research Council Protein Phosphorylation and Ubiquitylation Unit

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Neutrophil Protocol for Parkinson’s research into LRRK2 published

A protocol for utilizing human peripheral blood neutrophils for research into the Parkinson’s disease associated LRRK2 kinase has been published. The collaborative work led by Esther Sammler, Clinical Programme Leader in the Medical Research Council Protein Phosphorylation and Ubiquitylation Unit in the School and Clinical Senior Lecturer & Honorary Consultant in the School of Medicine.

Findlay lab makes new insights into tissue development from stem cells

New research by Greg Findlay’s group in the MRC-PPU has identified a signalling system that controls embryonic stem cell development, which has implications for understanding how tissues form within the mammalian embryo. The paper, by Rosalia Fernandez-Alonso and Francisco Bustos, post-doctoral investigators in Greg’s lab, uncovers a new role for the EPH-Ephrin system in regulating stem cell differentiation.

Postdoctoral Researcher

Summary of Job Purpose and Principal Duties

The Kulathu Lab at the MRC PPU, University of Dundee is looking to hire a Postdoctoral Researcher with strong expertise in biochemistry to address exciting questions about the mechanisms and function of the essential but poorly understood posttranslational modifier UFM1. The project is funded by a BBSRC grant awarded recently to the lab, and the position is available for 3 years.

Summary of Skills, Experience and Qualifications

Marie Skłodowska-Curie Early Stage Researcher

PhD position in the Innovative Training Network UBIMOTIF (ESR8):

Discovery and characterization of substrate recognition motifs of Deubiquitinases

Within the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement No 860517, the Kulathu lab at the MRC Protein Phosphorylation & Ubiquitylation Unit, University of Dundee is offering a 4 year PhD position for an Early Stage Researcher (ESR).

RSE honour for Life Sciences academics

Two Life Sciences academics who are helping transform lives with their work on major diseases including Parkinson’s and neglected tropical diseases such as malaria have been elected Fellows of the Royal Society of Edinburgh (RSE).

The RSE is Scotland’s national academy, focused on delivering its mission of `knowledge made useful’. Fellows are elected in recognition of their impact in improving the world around them.

New collaboration will harness latest technology to uncover role of proteins in neurodegenerative disease

A pioneering collaboration between the UK Dementia Research Institute (DRI) and the Medical Research Council’s Protein Phosphorylation and Ubiquitylation Unit (MRC PPU) will use the very latest advances in technology to study rare cell populations and the role of proteins in diseases such as Alzheimer’s and Parkinson’s.