University of Dundee

Postdoctoral Research Scientist

Cell Signalling and Immunology
Job Reference: 
Closing Date: 
Sunday, August 4, 2019
Grade 7 (£32,236 - £39,609)

Applications are invited for a postdoctoral researcher to work on an exciting collaborative project between the University of Dundee and Professor Bart De Strooper’s lab at the Dementia Research Institute. The successful applicant will work with Dr Andy Howden in the Division of Cell Signalling and Immunology in the School of Life Sciences in Dundee to characterise the proteome of microglial cells during Alzheimer’s disease. The project will use quantitative high-resolution mass spectrometry to map microglial proteomes during ageing and Alzheimer’s disease, generating novel data on the role of microglia in disease development. The School of Life Sciences at the University of Dundee has world-class mass spectrometry facilities, with cutting edge instrumentation and expertise in the use of proteomics to understand cell signalling. Close links with the Dementia Research Institute will be maintained throughout the project to plan experiments, develop ideas and share data.

School of Life Sciences

The School of Life Sciences at the University of Dundee is the highest-rated for Biological Sciences in the UK by the main standard of University research performance REF2014 ( Comprising about 100 research groups, the highest number of citations-per-paper for biological sciences in Europe (2013 and 2014 QS World University Rankings), over £100 million of research income in 2013 and nearly 900 staff from over 60 countries worldwide, the School enjoys a reputation as one of the most dynamic international centers for molecular cell biology, with outstanding laboratory and technology facilities. 'Lateral' and 'vertical' interactions within and between research groups are actively encouraged and 13% of publications in the past 5 years have been collaborations between two or more groups.

Diversity and equality of opportunity

The University of Dundee is a highly diverse community and is fully committed to equal opportunities for all, by providing a supportive, flexible and inclusive working environment. The School of Life Sciences is strongly committed to promoting equality and diversity amongst all our researchers. This included working with the local Athena SWAN charter to promote the recruitment and retention of women in STEMM subjects (science, technology, engineering, mathematics and medicine) in higher education and providing bespoke support for career development as required. The University of Dundee and the School of Life Sciences hold Athena SWAN Bronze Awards (, which recognises the importance we give to gender equality, and we have made further commitments to build an inclusive culture that supports and encourages all, including currently under-represented groups.

The University of Dundee has a range of family friendly policies, including flexible working, childcare vouchers, and a highly flexible approach to maternity and paternity leave. The University of Dundee also has staff groups for LGBT and BME, and prayer room facilities, and aims to promote a healthy work-life balance.

Candidate Requirements

• PhD with excellent academic track record

• Experience processing samples for mass spectrometry – cell lysis, protein digestion, peptide fractionation by HPLC

• Experience in the analysis of large complex proteomics data sets using established analysis platforms including MaxQuant and Perseus

• Enthusiasm to work in a team with close collaboration between institutes

• Experience working with immune cells would be advantageous

Appointment as a Postdoctoral Research Assistant on the Grade 7 salary scale is dependent upon you having been awarded a PhD. An appointment may be considered if you are shortly expected to be awarded a PhD. The initial appointment will be made as a Research Assistant on the Training Grade 7 salary scale (Spinal Point 28, £31,302).

The successful candidate should be a self-motivated, enthusiastic and skilled research scientist, with a strong background in biochemistry and proteomics. The successful candidate will participate in an interdisciplinary project, working together with immunologists and cell biologists from the collaborating research groups.

For further information about this position please contact Dr Andy Howden at

We are one of the UK’s leading universities – internationally recognised for our expertise across a range of disciplines and research breakthroughs in multiple areas, including science, medicine and engineering, amongst many others. Conveniently located on the banks of River Tay, our main city-centre campus is at the heart of Dundee - an up-and-coming, friendly, compact and affordable city with a rich heritage in design and technology. Just a short walk from the V&A Museum of Design Dundee, we’re close to both the train and bus stations. We also have campuses at Ninewells Hospital and in Kirkcaldy which are easily accessible via local transport links.

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The diversity of our staff and students helps to make the University of Dundee a UK university of choice for undergraduate, postgraduate and distance learning. Family friendly policies, staff networks for BME, Disabled and LGBT staff, membership of Athena SWAN, the ECU Race Equality Charter and Stonewall as well a full range of disability services, create an enjoyable and inclusive place to work.