University of Dundee

DMPK Project Lead

Drug Discovery Unit
Job Reference: 
Closing Date: 
Wednesday, October 23, 2019
Grade 6 (£26,715 - £32,817)

The Drug Discovery Unit (DDU) (see is a fully integrated drug discovery operation based within a world-class Life Sciences research environment. Our remit is to complement BioPharma activities by tackling both neglected disease drug discovery (leishmaniasis, Chagas disease, TB, Cryptosporidiosis and malaria) and validating novel drug targets across a range of therapeutics areas. The DDU works to Biotech style philosophy and standards incorporating, dynamic, goal driven project management based on Target Product Profiles and Compound Selection Criteria. The project goals are therapeutic area dependent but range from quality leads demonstrating disease model proof of concept, through to pre-clinical development candidates.

We are seeking a personable and enthusiastic individual to take up the post of junior Drug Metabolism and Pharmacokinetics (DMPK) in vitro scientist within the DDU. The successful applicant will work within the DMPK in vitro team in the DDU to provide in vitro DMPK assay support, contributing to drug discovery projects from the hit discovery phase through to lead optimisation and candidate selection.

You will have a minimum of a pharmacology related degree. Experience in drug discovery DMPK gained working in a drug discovery research and/or development environment, preferably within the BioPharmaceutical industry would be an advantage.

The post is available immediately, fixed term for 12 months. Salary will depend on experience, but will be between £26,715 - £32,817

Your responsibilities:

• Work within the DMPK in vitro team to provide in vitro DMPK support to all drug discovery programmes

• Help evaluate, develop and implement novel assays as required to build unit capability

• Carry out data analysis and relevant quality assurance

Required attributes:

• Professionally qualified with a minimum of a degree in pharmacology or a related topic

• Highly motivated with a strong proactive approach

• Excellent team working skills

• A willingness to work flexibly to meet project milestones

• Excellent time management and organisational skills

• Strong interpersonal and communication skills

Preferred attributes:

• Experience of carrying out in vitro DMPK support within a drug discovery or development project would be an advantage

• Knowledge of DMPK and understanding and appreciation of the drug discovery process would be an advantage

A few facts about The School of Life Sciences at Dundee:

• The School of Life Sciences has over 900 research and support staff from 59 countries and external funding in excess of £40 million per year.

• Dundee has twice been named ‘the best place to work in Europe’ in a poll of scientists conducted by The Scientist magazine.

• The School of Life Sciences has been consistently rated ‘5-star’ (the highest rating) by the UK national Research Assessment Exercise.

Dundee, set on the east coast of Scotland, lies in an area of outstanding natural beauty, including large sandy beaches and challenging hills. Dundee is also a vibrant cultural centre. Home to the new V&A Dundee, opened in September 2018 and already hosting its 500,000th visitor; the Dundee Rep and Scottish Dance Theatre; Dundee Contemporary Arts; MacManus Gallery and many individual artists.

For further information about the local area and the top reasons to live and work in Dundee and Scotland;

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The diversity of our staff and students helps to make the University of Dundee a UK university of choice for undergraduate, postgraduate and distance learning. Family friendly policies, staff networks for BME, Disabled and LGBT staff, membership of Athena SWAN, the ECU Race Equality Charter and Stonewall as well a full range of disability services, create an enjoyable and inclusive place to work.