Summary of Job Purpose and Principal Duties
The School of Life Sciences at the University of Dundee is a world-class academic institution with a reputation for the excellence of its research, its high quality teaching and student experience, and the strong impact of its activities outside academia. With 900 staff from over 60 countries worldwide the School provides a dynamic, multi-national, collegiate and diverse environment with state-of-the-art laboratory, technology and teaching facilities.
We are recruiting for an exceptional individual to join us as a post-doctoral research associate in the Bergkessel Laboratory, to investigate the regulation of biosynthetic activities during growth arrest in bacteria. This is a full-time position for up to 48 months, funded by a UKRI Future Leaders Fellowship grant.
Research in the Bergkessel Laboratory is focused on understanding the regulation of non-growing states of Pseudomonas aeruginosa and other Proteobacteria. Most bacteria in natural environments spend most of their time growing slowly or not at all due to stress or nutrient limitation, but almost all of our understanding of regulatory mechanisms comes from studies of a few model organisms growing rapidly in the lab. We aim to address this gap in understanding of bacterial physiology using approaches based in biochemistry, molecular genetics, and cell biology.
This position will provide a unique opportunity to contribute to a growing area of research in microbiology, with implications for important challenges like combatting the rise in resistance to currently used antibiotics and maximising potential benefits of microbial interactions with plants. The successful applicant will have the opportunity to develop the project collaboratively with the principal investigator, and to contribute to the mentoring of students. Travel to present research findings will be supported, once in-person conferences are able to resume.
Appointment as a Postdoctoral Research Assistant on the Grade 7 salary scale is dependent upon you having been awarded a PhD. An appointment may be considered if you are shortly expected to be awarded a PhD. In this case, the initial appointment would be made as a Research Assistant on the Training Grade 7 salary scale (Spinal Point 25 - 28 £29,176 - £31,866). Appointment will not be made higher than Spinal Point 31.
Summary of Skills, Experience and Qualifications
Your priorities will include:
- Using next-generation sequencing and proteomics based screens as well as more classical genetic methods to identify novel regulators of growth-arrested states.
- Using in vitro biochemistry and physiology assays to gain further mechanistic insight into the roles of the identified regulators.
- Keeping excellent records of all work and contributing to lab organisation and upkeep tasks.
- Communicating results to the international research community through publications and presentations
- Contributing to mentorship of students
Who we’re looking for:
- Must hold a PhD in Microbiology, Molecular Biology, Biochemistry, or related field by the start of the position
- Must have excellent communication and interpersonal skills
- Must have at least one research publication in an internationally-recognised, peer-reviewed journal
- Previous work should display evidence of ability to solve problems independently and contribute to a team
- Previous experience with processing next-generation sequencing data, genetic manipulation of Gram-negative bacteria, and/or purification of recombinant proteins desirable
For further information about this position please contact Megan Bergkessel at firstname.lastname@example.org. To find out more about the Molecular Microbiology Division in the School of Life Sciences please visit https://www.lifesci.dundee.ac.uk/research/mmb.
College / School / Directorate Information
We are one of the UK’s leading universities – internationally recognised for our expertise across a range of disciplines and research breakthroughs in multiple areas, including science, medicine and engineering, amongst many others. Conveniently located on the banks of River Tay, our main city-centre campus is at the heart of Dundee - an up-and-coming, friendly, compact and affordable city with a rich heritage in design and technology. Just a short walk from the V&A Museum of Design Dundee, we’re close to both the train and bus stations. We also have campuses at Ninewells Hospital and in Kirkcaldy which are easily accessible via local transport links.
The diversity of our staff and students helps to make the University of Dundee one of the top universities in the UK. Family friendly policies, staff support networks for BME and LGBT staff, membership of Athena Swan and Stonewall, as well a full range of disability services, create an enjoyable and inclusive place to work.