The School of Life Sciences at the University of Dundee is a world-class academic institution with a reputation for the excellence of its research, its high quality teaching and student experience, and the strong impact of its activities outside academia. With 900 staff from over 60 countries worldwide the School provides a dynamic, multi-national, collegiate and diverse environment with state-of-the-art laboratory, technology and teaching facilities.
We are recruiting for an exceptional individual to join us as a Postdoctoral Researcher within the research group led by Dr Henry McSorley, to carry out research on a Wellcome Investigator-funded project on IL-33 responses in local and systemic immune responses.
This position will involve working on an exciting Wellcome-funded project “Molecular regulators of the alarmin IL-33 in health and disease”. This project will involve investigation of the role of IL-33 in parasitic infection and obesity, focussing mainly on animal models, but also with some work on human samples. Experimental techniques will include intestinal organoid culture, single-cell RNAseq, proteomics, characterisation of new transgenic animal lines, parasite infections and immunological readouts (e.g. flow cytometry, advanced imaging techniques). This project will vastly expand our understanding of the role of IL-33 in vivo, how it can be controlled by both the parasite and the host, and how it acts both locally and systemically.
This position is an excellent opportunity to join a dynamic research group, and help to drive an exciting and cutting-edge research programme. The McSorley lab is a friendly and enthusiastic set of research scientists, with expertise in parasitology, immunology and molecular biology. We are looking for a candidate who will bring new skills to the group, and will have the ambition and determination to propel this project onwards and answer the research questions which we in the group are passionate about. You will have access to Dundee’s world-class research environment, which is open, collegiate and friendly, and has excellent facilities for meeting all parts of our research agenda.
- PhD in a relevant field such as Immunology, Infectious Disease, Molecular Biology or Cellular Biology
- Experience of immunology or cell biology research
- Technical expertise in flow cytometry or fluorescent imaging technique
- Experimental design experience and expertise
- An ambitious and driven candidate
- Ability to work in an interdisciplinary group, and manage collaborations
What we're looking for:
- Proteomic or scRNAseq experience
- Bioinformatic analyses or coding experience
- Organoid culture experience
- In vivo experimental design and implementation
- Parasite lifecycle maintenance.
We are one of the UK’s leading universities – internationally recognised for our expertise across a range of disciplines and research breakthroughs in multiple areas, including science, medicine and engineering, amongst many others. Conveniently located on the banks of River Tay, our main city-centre campus is at the heart of Dundee - an up-and-coming, friendly, compact and affordable city with a rich heritage in design and technology. Just a short walk from the V&A Museum of Design Dundee, we’re close to both the train and bus stations. We also have campuses at Ninewells Hospital and in Kirkcaldy which are easily accessible via local transport links.
The position is fixed-term for 36 months, and the appointment will be made on the University's Grade 7 salary scale between £32,817 - £34,804, depending on experience.
Appointment on the Grade 7 salary scale is dependent upon you having been awarded a PhD. An appointment may be considered if you are shortly expected to be awarded a PhD. In this case the initial appointment would be made as a Research Assistant on the Training Grade 7 salary scale (between £29,176 - £31,866).
For further information about this position please contact Dr Henry McSorley at firstname.lastname@example.org. To find out more about the McSorley lab, please visit https://www.lifesci.dundee.ac.uk/people/henry-mcsorley.
The University's statement on the use of animals in research can be found here: https://www.dundee.ac.uk/research/governance-policy/policyroadmap/statement-on-use-of-animals/
The diversity of our staff and students helps to make the University of Dundee a UK university of choice for undergraduate, postgraduate and distance learning. Family friendly policies, staff networks for BME, Disabled and LGBT staff, membership of Athena SWAN, the ECU Race Equality Charter and Stonewall as well a full range of disability services, create an enjoyable and inclusive place to work.