University of Dundee

Cell Biology and Immunology 2010

Cao, H. and Crocker, P. R. (2010) Evolution of CD33-related siglecs: regulating host immune functions and escaping pathogen exploitation? Immunology, 132, 18-26.

Chen, W. C., Completo, G. C., Sigal, D. S., Crocker, P. R., Saven, A. and Paulson, J. C. (2010) In vivo targeting of B-cell lymphoma with glycan ligands of CD22. Blood, 115, 4778-4786.

Cowling, V. H. (2010) Enhanced mRNA cap methylation increases cyclin D1 expression and promotes cell transformation. Oncogene, 29, 930-936.

Cowling, V. H. (2010) Myc up-regulates formation of the mRNA methyl cap. Biochem Soc Trans, 38, 1598-1601.

Cowling, V. H. and Cole, M. D. (2010) Myc Regulation of mRNA Cap Methylation. Genes Cancer, 1, 576-579.

Dissanayake, K., Toth, R., Blakey, J., Olsson, O., Campbell, D. G., Prescott, A. and Mackintosh, C. (2010) Erk/p90RSK/14-3-3 signalling impacts on expression of PEA3 Ets transcription factors via the transcriptional repressor capicua. Biochem J.

Dzamko, N., Deak, M., Hentati, F., Reith, A. D., Prescott, A. R., Alessi, D. R. and Nichols, R. J. (2010) Inhibition of LRRK2 kinase activity leads to dephosphorylation of Ser(910)/Ser(935), disruption of 14-3-3 binding and altered cytoplasmic localization. Biochem J, 430, 405-413.

Finlay, D. and Cantrell, D. Phosphoinositide 3-kinase and the mammalian target of rapamycin pathways control T cell migration. Ann N Y Acad Sci, 1183, 149-157.

Finlay, D. and Cantrell, D. (2010) The Coordination of T-cell Function by Serine/Threonine Kinases. Cold Spring Harb Perspect Biol.

Finlay, D. K., Kelly, A. P., Clarke, R., Sinclair, L. V., Deak, M., Alessi, D. R. and Cantrell, D. A. (2010) Temporal differences in the dependency on phosphoinositide-dependent kinase 1 distinguish the development of invariant Valpha14 NKT cells and conventional T cells. J Immunol, 185, 5973-5982.

Gawden-Bone, C., Zhou, Z., King, E., Prescott, A., Watts, C. and Lucocq, J. (2010) Dendritic cell podosomes are protrusive and invade the extracellular matrix using metalloproteinase MMP-14. J Cell Sci, 123, 1427-1437.

Heikema, A. P., Bergman, M. P., Richards, H., Crocker, P. R., Gilbert, M., Samsom, J. N., van Wamel, W. J., Endtz, H. P. and van Belkum, A. (2010) Characterization of the specific interaction between sialoadhesin and sialylated Campylobacter jejuni lipooligosaccharides. Infect Immun, 78, 3237-3246.

Hurtado-Guerrero, R., Zusman, T., Pathak, S., Ibrahim, A. F., Shepherd, S., Prescott, A., Segal, G. and van Aalten, D. M. (2010) Molecular mechanism of elongation factor 1A inhibition by a Legionella pneumophila glycosyltransferase. Biochem J, 426, 281-292.

Khatua, B., Ghoshal, A., Bhattacharya, K., Mandal, C., Saha, B., Crocker, P. R. and Mandal, C. (2010) Sialic acids acquired by Pseudomonas aeruginosa are involved in reduced complement deposition and siglec mediated host-cell recognition. FEBS Lett, 584, 555-561.

Lucocq, J. M. and Gawden-Bone, C. (2010) Quantitative assessment of specificity in immunoelectron microscopy. J Histochem Cytochem, 58, 917-927.

Matthews, S. A., Navarro, M. N., Sinclair, L. V., Emslie, E., Feijoo-Carnero, C. and Cantrell, D. A. (2010) Unique functions for protein kinase D1 and protein kinase D2 in mammalian cells. Biochem J, 432, 153-163.

Matthews, S. P., Werber, I., Deussing, J., Peters, C., Reinheckel, T. and Watts, C. (2010) Distinct protease requirements for antigen presentation in vitro and in vivo. J Immunol, 184, 2423-2431.

Mattock, K. L., Gough, P. J., Humphries, J., Burnand, K., Patel, L., Suckling, K. E., Cuello, F., Watts, C., Gautel, M., Avkiran, M. and Smith, A. (2010) Legumain and cathepsin-L expression in human unstable carotid plaque. Atherosclerosis, 208, 83-89.

Nichols, R. J., Dzamko, N., Morrice, N. A., Campbell, D. G., Deak, M., Ordureau, A., Macartney, T., Tong, Y., Shen, J., Prescott, A. R. and Alessi, D. R. (2010) 14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization. Biochem J, 430, 393-404.

Tamas, P., Macintyre, A., Finlay, D., Clarke, R., Feijoo-Carnero, C., Ashworth, A. and Cantrell, D. (2010) LKB1 is essential for the proliferation of T-cell progenitors and mature peripheral T cells. Eur J Immunol, 40, 242-253.

Van Breedam, W., Van Gorp, H., Zhang, J. Q., Crocker, P. R., Delputte, P. L. and Nauwynck, H. J. (2010) The M/GP(5) glycoprotein complex of porcine reproductive and respiratory syndrome virus binds the sialoadhesin receptor in a sialic acid-dependent manner. PLoS Pathog, 6, e1000730.

Watts, C., West, M. A. and Zaru, R. (2010) TLR signalling regulated antigen presentation in dendritic cells. Curr Opin Immunol, 22, 124-130.

Zagorska, A., Deak, M., Campbell, D. G., Banerjee, S., Hirano, M., Aizawa, S., Prescott, A. R. and Alessi, D. R. (2010) New roles for the LKB1-NUAK pathway in controlling myosin phosphatase complexes and cell adhesion. Sci Signal, 3, ra25.