University of Dundee

Centres, Divisions & Units

  • The overarching theme of the Division is "the discovery of chemical solutions to biological problems" through excellence in basic and applied multidisciplinary research.

  • Researchers in this Division investigate the mechanisms of differentiation in developing organisms, stem cells and adult tissues and how these are corrupted in disease states.

  • The Division of Cell Signalling and Immunology hosts research groups whose work is relevant to the pathologies associated with cancer, diabetes, infectious disease, autoimmunity and allergy.

  • The Centre for Antimicrobial Resistance at the University of Dundee brings together biologists, chemists, physicists, clinicians, mathematicians, epidemiologists, engineers and designers to focus on innovation in tackling antimicrobial resistance.

  • The Centre for Gene Regulation and Expression (GRE) was created within the University of Dundee School of Life Sciences in January 2008. Our aim is to build and enhance GRE as a world leading research centre studying the cell biology of gene expression and chromosome biology.

  • Targeted protein degradation is an entirely new approach that is revolutionising drug discovery by making the treatment of diseases previously thought to be undruggable a reality. The CeTPD is bolstering Dundee’s world-leading position in this field that is revolutionising drug discovery.

  • The Division of Computational Biology brings together scientists with skills in developing and applying computational, mathematical and biophysical techniques to questions in biological and medical research.

  • The Dundee Drug Discovery Unit (DDU) was founded in 2006 with the aim of translating basic science into lead compounds to validate putative drug targets, to use as tools to investigate disease pathways and, when appropriate, advance to pre-clinical drug candidates.

  • The Geomicrobiology Group carries out research on the geoactive properties of microorganisms in order to understand their importance in key biosphere processes and their applied potential.

  • The MRC Protein Phosphorylation and Ubiquitylation Unit (PPU) is a major research centre that focuses on the understanding of the biological roles of phosphorylation and ubiquitylation and how disruption of these processes cause human diseases such as neurodegeneration, cancer, hypertension and immune disorders.

  • The Division of Molecular Microbiology encompasses a spectrum of research that flows from fundamental science using model organisms to translational research on medically- and economically-significant pathogens. The overarching purpose of the Division is to further the science of Molecular Microbiology through excellent, innovative and internationally-recognised research on a broad platform of topics. These topics currently include: molecular determinants of bacterial virulence; host responses to microbial pathogens; fundamental physiological processes in microbial cells, including transport and generation of the cell surface; inter-bacterial interactions; and identification of potential targets for antimicrobial intervention and biotechnological applications.

  • The work of the group centres on the structural, dynamic and chemical properties of nucleic acids, and their recognition by and interactions with proteins. Nucleic acids perform many roles in the cell. They act as the store of genetic information (DNA), the genetic messenger and template for the synthesis of proteins (mRNA), the processing of mature spliced RNA (snRNA) and precisely processed RNA (snoRNA), as an enzyme (ribozymes, including peptidyl transferase activity of the ribosome) and even in the control of gene expression (miRNA species, and riboswitches).

  • Plants form the basis of life on Earth providing food to sustain human and animal life, as well as being exploited for natural products and medicine. They are essential to the atmosphere in fixing carbon and releasing oxygen. The importance of plant sciences to the world’s ecosystems is highlighted by the current concerns over climate change and fuel and food security.

  • Wellcome Centre for Anti-Infectives Research (WCAIR) brings together the Drug Discovery Unit, the Mode of Action group and the Parasitology research groups providing an integrated pathway from discovery science to pre-clinical candidate selection.

  • The National Phenotypic Screening Centre (NPSC) is an advanced high throughput facility that brings technology to the biology by focussing on the development and screening of physiologically-relevant assays to tackle human, animal and plant diseases.