University of Dundee

Cell Signalling and Immunology 2020

Bozic M, van den Bekerom L, Milne BA, Goodman N, Roberston L, Prescott A, Macartney T, Dawe N, McEwan D. 2020. A conserved ATG2-GABARAP family interaction is critical for phagophore formation. EMBO Reports. 21(3):1-17. https://doi.org/10.15252/embr.201948412

Chauché C, Vacca F, Chia SL, Richards J, Gregory WF, Ogunkanbi A, Wear MA, McSorley HJ. 2020. A Truncated Form of HpARI Stabilizes IL-33, Amplifying Responses to the Cytokine. Frontiers in Immunology. 11:Article 1363. https://doi.org/10.3389/fimmu.2020.01363

Damasio MP, Marchingo JM, Spinelli L, Hukelmann JL, Cantrell DA, Howden AJM. 2020. Extracellular signal-regulated kinase (ERK) pathway control of CD8+ T cell differentiation. Biochemical Journal. https://doi.org/10.1042/BCJ20200661

Di Carluccio C, Crisman E, Manabe Y, Forgione RE, Lacetera A, Amato J, Pagano B, Randazzo A, Zampella A, Lanzetta R, Fukase K, Molinaro A, Crocker PR, Martín-Santamaría S, Marchetti R, Silipo A. 2020. Characterisation of the Dynamic Interactions between Complex N-Glycans and Human CD22. ChemBioChem. 21(1-2):129-140. https://doi.org/10.1002/cbic.201900295

Di Carluccio C, Forgione RE, Molinaro A, Crocker PR, Marchetti R, Silipo A. 2020. Exploring the fascinating world of sialoglycans in the interplay with Siglecs. Rauter AP, Lindhorst TK, Queneau Y, editors. In Carbohydrate Chemistry: Chemical and Biological Approaches. Royal Society of Chemistry. pp. 31-55. (SPR - Carbohydrate Chemistry). https://doi.org/10.1039/9781788013864-00031

Evans AM, Hardie DG. 2020. AMPK and the Need to Breathe and Feed: What's the Matter with Oxygen?. International Journal of Molecular Sciences. 21(10):1-28. https://doi.org/10.3390/ijms21103518

Floyd A, Yeoman H, Southern J, Dillon R, Cook S, Fairlamb A, Ferguson M, Horn D, MacLean L, Manthri S, Paterson C, Pearson L, Prescott A, Read K, Shastry L, Svensen N, Thomas J. 2020. Para-site-seeing: Exhibition Catalogue. University of Dundee: University of Dundee. [Exhibition catalogue]. https://doi.org/10.20933/100001171

Forgione RE, Di Carluccio C, Guzmán-Caldentey J, Gaglione R, Battista F, Chiodo F, Manabe Y, Arciello A, Del Vecchio P, Fukase K, Molinaro A, Martín-Santamaría S, Crocker PR, Marchetti R, Silipo A. 2020. Unveiling Molecular Recognition of Sialoglycans by Human Siglec-10. iScience. 23(6):1-29. https://doi.org/10.1016/j.isci.2020.101231

González A, Hall MN, Lin S-C, Hardie G. 2020. AMPK and TOR: the Yin and Yang of cellular nutrient sensing and growth control. Cell Metabolism. 31(3):472-492. https://doi.org/10.1016/j.cmet.2020.01.015

Gorby C, Sotolongo Bellón J, Wilmes S, Warda W, Pohler E, Fyfe PK, Cozzani A, Ferrand C, Walter MR, Mitra S, Piehler J, Moraga I. 2020. Engineered IL-10 variants elicit potent immunomodulatory effects at low ligand doses. Science Signaling. 13(649):Article eabc0653. https://doi.org/10.1126/scisignal.abc0653

Hardie DG. 2020. AMPK as a direct sensor of long-chain fatty acyl–CoA esters. Nature Metabolism. https://doi.org/10.1038/s42255-020-0249-y

Hawley SA, Ross FA, Russell FM, Atrih A, Lamont D, Hardie DG. 2020. Mechanism of Activation of AMPK by Cordycepin. Cell Chemical Biology. 27(2):214-222.e4. https://doi.org/10.1016/j.chembiol.2020.01.004

Ibrahim AFM, Shen L, Tatham MH, Dickerson D, Prescott AR, Abidi N, Xirodimas DP, Hay RT. 2020. Antibody RING-Mediated Destruction of Endogenous Proteins. Molecular Cell. 79(1):155-166. https://doi.org/10.1016/j.molcel.2020.04.032

James OJ, Vandereyken M, Swamy M. 2020. Isolation, Characterization, and Culture of Intestinal Intraepithelial Lymphocytes. Amarnath S, editor. In Innate Lymphoid Cells: Methods and Protocols. New York: Humana Press. pp. 141-152. (Methods in Molecular Biology). https://doi.org/10.1007/978-1-0716-0338-3_13

Lawal HM, Schilde C, Kin K, Brown MW, James J, Prescott AR, Schaap P. 2020. Cold climate adaptation is a plausible cause for evolution of multicellular sporulation in Dictyostelia. Scientific Reports. 10(1):1-9. https://doi.org/10.1038/s41598-020-65709-3

Marchingo J, Sinclair L, Howden A, Cantrell D. 2020. Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation. eLife. 9:1-23. https://doi.org/10.7554/eLife.53725

Marchingo JM, Cantrell DA. 2020. The active inner life of naïve T cells. Nature Immunology. 21(8):827-828. https://doi.org/10.1038/s41590-020-0726-1

Martinez-Fabregas J, Wang L, Pohler E, Cozzani A, Wilmes S, Kazemian M, Mitra S, Moraga I. 2020. CDK8 Fine-Tunes IL-6 Transcriptional Activities by Limiting STAT3 Resident Time at the Gene Loci. Cell Reports. 33(12):Article 108545. https://doi.org/10.1016/j.celrep.2020.108545

McSorley H, Johansson K. 2020. Reply to comment from Carl Persson. Pediatric Allergy and Immunology. 31(3):338-339. https://doi.org/10.1111/pai.13214

Meakin PJ, Coull BM, Tuharska Z, McCaffery C, Akoumianakis I, Antoniades C, Brown J, Griffin KJ, Platt F, Ozber CH, Yuldasheva NY, Makava N, Skromna A, Prescott AR, McNeilly AD, Siddiqui MK, Palmer CNA, Khan F, Ashford MLJ. 2020. Elevated circulating amyloid concentrations in obesity and diabetes promote vascular dysfunction. Journal of Clinical Investigation. 130(8):4104-4117. https://doi.org/10.1172/JCI122237

Murugesan G, Correia VG, Palma AS, Chai W, Li C, Feizi T, Martin E, Laux B, Franz A, Fuchs K, Weigle B, Crocker PR. 2020. Siglec-15 recognition of sialoglycans on tumor cell lines can occur independently of sialyl Tn antigen expression. Glycobiology. 1-11. https://doi.org/10.1093/glycob/cwaa048

Nisr R, Shah D, Hundal H. 2020. Mono- and Polyunsaturated Fatty Acids Counter Palmitate-Induced Mitochondrial Dysfunction in Rat Skeletal Muscle Cells. Cellular Physiology and Biochemistry. 54(5):975-993. https://doi.org/10.33594/000000282

Obst J, Simon E, Martin-Estebane M, Pipi E, Barkwill LM, Gonzalez-Rivera I, Buchanan F, Prescott AR, Faust D, Fox S, Brownlees J, Taylor D, Perry VH, Nuthall H, Atkinson PJ, Karran E, Routledge C, Gomez-Nicola D. 2020. Inhibition of IL-34 Unveils Tissue-Selectivity and Is Sufficient to Reduce Microglial Proliferation in a Model of Chronic Neurodegeneration. Frontiers in Immunology. 11:Article 579000. https://doi.org/10.3389/fimmu.2020.579000

Olateju OI, Morè L, Arthur JSC, Frenguelli BG. 2020. Mitogen and Stress-activated Protein Kinase 1 negatively regulates hippocampal neurogenesis. Neuroscience. https://doi.org/10.1016/j.neuroscience.2020.11.017

Pattison MJ, Naik RJ, Reyskens KMSE, Arthur JSC. 2020. Loss of Mef2D function enhances TLR induced IL-10 production in macrophages. Bioscience Reports. 40(8):1-15. https://doi.org/10.1042/BSR20201859

Petrova T, Pesic J, Pardali K, Gaestel M, Arthur JSC. 2020. p38 MAPK signalling regulates cytokine production in IL-33 stimulated Type 2 Innate Lymphoid cells. Scientific Reports. 10:Article 3479. https://doi.org/10.1038/s41598-020-60089-0

Privitera L, Morè L, Cooper DD, Richardson P, Tsogka M, Hebenstreit D, Arthur JSC, Frenguelli BG. 2020. Experience recruits MSK1 to expand the dynamic range of synapses and enhance cognition. Journal of Neuroscience. 40(24):4644-4660. https://doi.org/10.1523/JNEUROSCI.2765-19.2020

Rosazza T, Warner J, Sollberger G. 2020. NET formation - mechanisms and how they relate to other cell death pathways. FEBS Journal. https://doi.org/10.1111/febs.15589

Ross S, Cantrell D. 2020. Of Mosaicism and Mechanisms: How JAK1 variant goes awry. Immunity. 53(3):481-484. https://doi.org/10.1016/j.immuni.2020.08.010

Seabright AP, Fine NHF, Barlow JP, Lord SO, Musa I, Gray A, Bryant JA, Banzhaf M, Lavery GG, Hardie DG, Hodson DJ, Philp A, Lai Y-C. 2020. AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1-Parkin independent manner. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34(5):6284-6301. https://doi.org/10.1096/fj.201903051R

Shah D, Nisr R, Stretton C, Krasteva-Christ G, Hundal H. 2020. Caveolin-3 deficiency associated with the dystrophy P104L mutation impairs skeletal muscle mitochondrial form and function. Journal of Cachexia, Sarcopenia and Muscle. 11(3):838-858. https://doi.org/10.1002/jcsm.12541

Sinclair LV, Barthelemy C, Cantrell DA. 2020. Single Cell Glucose Uptake Assays: A Cautionary Tale. Immunometabolism. 2(4):Article e200029. https://doi.org/10.20900/immunometab20200029

Sollberger G, Streeck R, Apel F, Caffrey BE, Skoultchi AI, Zychlinsky A. 2020. Linker histone H1.2 and H1.4 affect the neutrophil lineage determination. eLife. 9:1-24. https://doi.org/10.7554/eLife.52563

Vacca F, Chauché C, Jamwal A, Hinchy EC, Heieis G, Webster H, Ogunkanbi A, Sekne Z, Gregory WF, Wear MA, Perona-Wright G, Higgins MK, Nys J, Cohen ES, McSorley HJ. 2020. A helminth-derived suppressor of ST2 blocks allergic responses. eLife. 9:1-20. https://doi.org/10.7554/eLife.54017

Vandereyken M, James O, Swamy M. 2020. Mechanisms of activation of innate-like intraepithelial T lymphocytes. Mucosal Immunology. 13(5):721-731. https://doi.org/10.1038/s41385-020-0294-6

Vara-ciruelos D, Dandapani M, Hardie DG. 2020. AMP-Activated Protein Kinase: Friend or Foe in Cancer. Annual Review of Cancer Biology. 4:1-16. https://doi.org/10.1146/annurev-cancerbio-030419-033619

Wilmes S, Hafer M, Vuorio J, Tucker JA, Winkelmann H, Löchte S, Stanly TA, Pulgar Prieto KD, Poojari C, Sharma V, Richter CP, Kurre R, Hubbard SR, Garcia KC, Moraga I, Vattulainen I, Hitchcock IS, Piehler J. 2020. Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations. Science. 367(6478):643-652. https://doi.org/10.1126/science.aaw3242

Yamakawa N, Yasuda Y, Yoshimura A, Goshima A, Crocker PR, Vergoten G, Nishiura Y, Takahashi T, Hanashima S, Matsumoto K, Yamaguchi Y, Tanaka H, Kitajima K, Sato C. 2020. Discovery of a new sialic acid binding region that regulates Siglec-7. Scientific Reports. 10(1):1-14. https://doi.org/10.1038/s41598-020-64887-4

Zhang CS, Hardie DG, Lin SC. 2020. Glucose Starvation Blocks Translation at Multiple Levels. Cell Metabolism. 31(2):217-218. https://doi.org/10.1016/j.cmet.2020.01.005